Risks and Limitations of DNA Analysis

  • Uncertain Variants or Unanticipated Results:
  • Genetic testing can sometimes reveal variants of uncertain significance, leading to ambiguous results that complicate clinical decision-making.
  • False Negatives and Positives:
  • There is a risk of receiving false negative or positive findings, which could lead to misinformed health management decisions.
  • Lack of Established Management Guidelines:
  • For some genetic conditions, there may be an absence of clear guidelines on how to best manage or treat the condition, leaving patients and healthcare providers in a challenging position.
  • Unpredictability of Future Health:
  • While genetic testing can provide risk assessments for certain conditions, it cannot predict future health outcomes with certainty, leaving an element of unpredictability.
  • Emotional Impact:
  • The knowledge gained from genetic testing can cause anxiety, stress, or emotional distress, impacting mental health.
  • Family Dynamics:
  • Discovering genetic information can sometimes lead to feelings of blame, guilt, or secrecy within families, affecting relationships.
  • Discrimination Concerns:
  • Individuals may have concerns about genetic discrimination in areas like employment or insurance, despite legal protections.

 

For those seeking more information on protections against genetic discrimination, the Genetic Information Nondiscrimination Act (GINA) provides a legal framework. It’s advisable to consult a discussion guide on GINA to understand your rights and the protections it offers.

Please use the form below to contact MoodNote if you have questions, would like to place a data interpretation order or would like to schedule an appointment with a genomics-trained physician.



    
     
   

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